Harlequin-Type Ichthyosis

Level 1 – Surface Web
MEDICINE

Harlequin-type ichthyosis is a genetic disorder that results in thickened skin over nearly the entire body at birth.[4] The skin forms large, diamond-shaped plates that are separated by deep cracks.[4] These affect the shape of the eyelids, nose, mouth, and ears and limit movement of the arms and legs.[4] Restricted movement of the chest can lead to breathing difficulties.[4] These plates fall off over several weeks.[3] Other complications can include premature birth, infection, problems with body temperature, and dehydration.[4][5] The condition is the most severe form of ichthyosis, a group of genetic disorders characterised by scaly skin.

LINKS
http://en.wikipedia.org/wiki/Harlequin-type_ichthyosis